Expression and catalytic properties of rat liver nadp-isocitrate dehydrogenase under normal conditions, after administration of tumor necrosis factor-α and at thioctic acid action
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چکیده
منابع مشابه
Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes.
The structures of NADP+ and magnesium isocitrate bound to the NADP(+)-dependent isocitrate dehydrogenase of Escherichia coli have been determined and refined at 2.5-A resolution. NADP+ is bound by the large domain of isocitrate dehydrogenase, a structure that has little similarity to the supersecondary structure of the nucleotide-binding domain of the lactate dehydrogenase-like family of nucleo...
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ژورنال
عنوان ژورنال: Biomeditsinskaya Khimiya
سال: 2010
ISSN: 2310-6905,2310-6972
DOI: 10.18097/pbmc20105602220